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Adiposis dolorosa
Synonym:
Dercum's disease
Adiposis dolorosa consists of chronic progressive, painful, sometimes ecchymotic plaques of fat. It is often associated with obesity, sometimes associated with systemic symptoms, including emotional upset.
Treatment:
- Intravenous lidocaine has induced remission in some cases.
More Information:
If you would like more information about this skin condition we recommend the following article by Dr. Karen L. HERBST:
Rare adipose disorders (RADs) masquerading as obesity
ABSTRACT:
Rare adipose disorders (RADs) including multiple symmetric lipomatosis (MSL), lipedema and Dercum’s disease (DD) may be misdiagnosed
as obesity. Lifestyle changes, such as reduced caloric intake and increased physical activity are standard care for obesity.
Although lifestyle changes and bariatric surgery work effectively for the obesity component of RADs, these treatments do not routinely
reduce the abnormal subcutaneous adipose tissue (SAT) of RADs. RAD SAT likely results from the growth of a brown stem cell population
with secondary lymphatic dysfunction in MSL, or by primary vascular and lymphatic dysfunction in lipedema and DD. People with
RADs do not lose SAT from caloric limitation and increased energy expenditure alone. In order to improve recognition of RADs apart
from obesity, the diagnostic criteria, histology and pathophysiology of RADs are presented and contrasted to familial partial lipodystrophies,
acquired partial lipodystrophies and obesity with which they may be confused.
Treatment recommendations focus on evidencebased
data and include lymphatic decongestive therapy, medications and supplements that support loss of RAD SAT. Associated RAD
conditions including depression, anxiety and pain will improve as healthcare providers learn to identify and adopt alternative treatment
regimens for the abnormal SAT component of RADs. Effective dietary and exercise regimens are needed in RAD populations to improve
quality of life and construct advanced treatment regimens for future generations.
Read full article
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